Leading the way to new and better cancer treatments

About Polaris

Polaris Group is a multinational biotechnology company focused on developing novel anti-cancer therapies.
Our lead drug candidate, Pegargiminase (ADI‑PEG 20), is a biologic in late-stage clinical development for a wide range of cancers, including hepatocellular carcinoma, mesothelioma, pancreatic cancer, non-small cell lung cancer, melanoma, acute myeloid leukemia and others.

Polaris Group is involved in every stage of the drug development process. Our family of companies harnesses structure-based drug design technology to create novel oncology therapies, conducts clinical studies at top-tier cancer centers worldwide and operates cGMP Production Facilities in Northern California and China.

Clinical Trials

Pegargiminase is in clinical development for numerous oncology indications.
Mesothelioma
Phase 3
Soft Tissue Sarcoma
Phase 3
Glioblastoma
Phase 1/2
Hepatic Cell Carcinoma
Phase 2/3
Acute Myeloid Leukemia
Phase 1

Development and Manufacturing Capabilities

Company News

English

The Polaris Pharmaceutical’s new drug for mesothelioma has increased the three-year survival rate by fourfold, as published in the internationally renowned medical journal JAMA Oncology.

The breakthrough clinical trial of a rare and aggressive cancer treatment reveals: Polaris metabolic therapy drug, ADI-PEG 20, presents an innovative treatment approach that significantly enhances the survival rates of patients with malignant pleural mesothelioma (MPM), particularly demonstrating a fourfold increase in three-year survival rates compared to the placebo group.

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English

Polaris Group Announced the Acquisition of Genovior Biotech, Initiating Dual- Engine Growth

TAIPEI, Taiwan and SAN DIEGO, Calif., Dec 21- Polaris Group (TWSE: 6550) announced that its board approved to increase the acquisition of Genovior Biotech’s shares to
100%. Additionally, Dr. Steve Hsu, Chairman of Genovior Biotech Corporation, has been appointed as the CEO of Polaris Group. This significant decision not only allows
Polaris Group to expand the product pipeline beyond its novel cancer metabolism therapy but also marks its entry into the highly promising realm of peptide drugs, such as the widely recognized Semaglutide-related products. These two highly
prospective product lines will serve as the dual engines propelling Polaris Group’s future growth.

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English

Polaris Group Initiates Phase 3 Trial: First Patient Successfully Dosed with ADI-PEG 20/Placebo plus Gemcitabine and Docetaxel for Difficult-to-Treat Leiomyosarcoma (LMS)

TAIPEI, Taiwan and SAN DIEGO, Calif., Nov 30 – Polaris Group (The Company, TWSE:6550), today announced that the first patient is successfully dosed in a pivotal Phase 3 trial that combines ADI-PEG 20 or placebo with traditional chemotherapy as systemic treatment in the second or third line for LMS.

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English

Polaris Group Announces First Patient Successfully Dosed with ADI-PEG 20/Placebo in Phase 2a Non-Alcoholic Steatohepatitis (NASH) Study

TAIPEI, Taiwan and SAN DIEGO, Calif., November 29— Polaris Group (The Company, TWSE:6550), today announced that the first patient was successfully dosed in the Phase 2a clinical study for Non-Alcoholic Steatohepatitis (NASH).

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